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Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.

Most DNA polymerases are multifunctional proteins that possess both polymerizing and exonucleolytic activities. For Escherichia coli DNA polymerase I and its relatives, polymerase and exonuclease activities reside on distinct, separable domains of the same polypeptide. The catalytic subunits of the...

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Bibliografische gegevens
Hoofdauteurs: Gibbs, J S, Weisshart, K, Digard, P, deBruynKops, A, Knipe, D M, Coen, D M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1991
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC361382/
https://ncbi.nlm.nih.gov/pubmed/1652064
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