Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.

Most DNA polymerases are multifunctional proteins that possess both polymerizing and exonucleolytic activities. For Escherichia coli DNA polymerase I and its relatives, polymerase and exonuclease activities reside on distinct, separable domains of the same polypeptide. The catalytic subunits of the...

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Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Gibbs, J S, Weisshart, K, Digard, P, deBruynKops, A, Knipe, D M, Coen, D M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361382/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1652064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.9.4786-4795.1991
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