A germline variant N375S in MET and gastric cancer susceptibility in a Chinese population

MET tyrosine kinase and its ligand, hepatocyte growth factor (HGF), play a pivotal role in the activties of tumor cells. A germline missense variant in exon 2 of the MET gene, N375S (rs33917957 A>G), may alter the binding affinity of MET for HGF and thus modify the risk of tumorigenesis. In this...

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Detalhes bibliográficos
Main Authors: Liu, Yao, Zhang, Qin, Ren, Chuanli, Ding, Yanbing, Jin, Guangfu, Hu, Zhibin, Xu, Yaochu, Shen, Hongbing
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2012
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613728/
https://ncbi.nlm.nih.gov/pubmed/23554766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.26.20110087
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