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Systematical analyses of variants in CTCF-binding sites identified a novel lung cancer susceptibility locus among Chinese population

Genome-wide association studies identified genetic susceptibility variants mostly lie outside of protein-coding regions. It suggested variants located at transcriptional regulatory region should play an important role in cancer carcinogenesis including lung cancer. In the present study, we systemati...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Dai, Juncheng, Zhu, Meng, Wang, Cheng, Shen, Wei, Zhou, Wen, Sun, Jie, Liu, Jia, Jin, Guangfu, Ma, Hongxia, Hu, Zhibin, Lin, Dongxin, Shen, Hongbing
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296290/
https://ncbi.nlm.nih.gov/pubmed/25592173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07833
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