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Dolichol phosphate mannose synthase is required in vivo for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and N glycosylation of protein in Saccharomyces cerevisiae.

Glycosyl phosphatidylinositol (GPI) anchoring, N glycosylation, and O mannosylation of protein occur in the rough endoplasmic reticulum and involve transfer of precursor structures that contain mannose. Direct genetic evidence is presented that dolichol phosphate mannose (Dol-P-Man) synthase, which...

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Bibliographic Details
Published in:Mol Cell Biol
Main Author: Orlean, P
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361358/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2146492/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.11.5796
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