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A Universal Scaling Law Determines Time Reversibility and Steady State of Substitutions under Selection

Monomorphic loci evolve through a series of substitutions on a fitness landscape. Understanding how mutation, selection, and genetic drift drive this process, and uncovering the structure of the fitness landscape from genomic data are two major goals of evolutionary theory. Population genetics model...

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Detalhes bibliográficos
Main Authors: Manhart, Michael, Haldane, Allan, Morozov, Alexandre V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613437/
https://ncbi.nlm.nih.gov/pubmed/22838027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2012.03.007
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