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Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice
The motheaten mouse has long served as a paradigm for complex autoimmune and inflammatory disease. Null mutations in Ptpn6, which encodes the non-receptor protein-tyrosine phosphatase Shp1, cause the motheaten phenotype. However, Shp1 regulates multiple signaling pathways in different hematopoietic...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613338/ https://ncbi.nlm.nih.gov/pubmed/23521885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.02.018 |
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