טוען...
Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis
The IL12B gene encodes the common p40 subunit of IL-12 and IL-23, cytokines with key roles in Th1 and Th17 biology, respectively, and genetic variation in this region significantly influences risk of psoriasis. Here, we demonstrate that a psoriasis-associated risk haplotype at the IL12B locus leads...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613166/ https://ncbi.nlm.nih.gov/pubmed/23376980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt034 |
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