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Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses

Host antibacterial responses include mechanisms that kill bacteria, but also those that protect or tolerize the host to potentially damaging antibacterial effects. We determined that Chitinase 3-like-1 (Chi3l1), a conserved prototypic chitinase-like protein, is induced by Streptococcus pneumoniae an...

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Bibliographic Details
Main Authors: Cruz, Charles S. Dela, Liu, Wei, He, Chuan Hua, Jacoby, Adam, Gornitzky, Alex, Ma, Bing, Flavell, Richard, Lee, Chun Geun, Elias, Jack A.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613130/
https://ncbi.nlm.nih.gov/pubmed/22817986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.05.017
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