CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli.

Ítems similars

• Development of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck mice
  per: Baker, Matthew, et al.
  Publicat: (2000)
• Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells.
  per: Stover, D R, et al.
  Publicat: (1991)
• Surface expression of a heterologous phosphatase complements CD45 deficiency in a T cell clone
  Publicat: (1994)
• Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase- deficient mice
  Publicat: (1995)
• Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.
  per: Koretzky, G A, et al.
  Publicat: (1991)