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Methylation Profiling Defines an Extensive Field Defect in Histologically Normal Prostate Tissues Associated with Prostate Cancer

Prostate cancer (PCa) is typically found as a multifocal disease suggesting the potential for molecular defects within the morphologically normal tissue. The frequency and spatial extent of DNA methylation changes encompassing a potential field defect are unknown. A comparison of non-tumor-associate...

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Autors principals: Yang, Bing, Bhusari, Sachin, Kueck, Jessica, Weeratunga, Pushpa, Wagner, Jennifer, Leverson, Glen, Huang, Wei, Jarrard, David F
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612912/
https://ncbi.nlm.nih.gov/pubmed/23555185
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