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The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat

Oval cell activation occurs under conditions of severe liver injury when normal hepatocyte proliferation is blocked. Recent studies have shown that a subset of hepatocellular carcinomas expresses oval cell markers, suggesting that these cells are targets of hepatocarcinogens. However, the signaling...

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Detalhes bibliográficos
Main Authors: Sanders, Jennifer A., Brilliant, Kate E., Clift, Danielle, Patel, Ajay, Cerretti, Bruno, Claro, Patricia, Mills, David R., Hixson, Douglas C., Gruppuso, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612884/
https://ncbi.nlm.nih.gov/pubmed/22525806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.04.002
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