טוען...
Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling
The transcription factor Ikaros regulates the development of hematopoietic cells. Ikaros-deficient animals fail to develop B cells and display a T-cell malignancy, which is correlated with altered Notch signaling. Recently, loss of Ikaros was associated with progression of myeloproliferative neoplas...
שמור ב:
| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612856/ https://ncbi.nlm.nih.gov/pubmed/23335373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-450627 |
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