A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment of type 2 diabetes mellitus

OBJECTIVES: To develop a longitudinal statistical model to indirectly estimate the comparative efficacies of two drugs, using model-based meta-analysis (MBMA). Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment w...

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Detalhes bibliográficos
Main Authors: Gross, Jorge Luiz, Rogers, James, Polhamus, Daniel, Gillespie, William, Friedrich, Christian, Gong, Yan, Monz, Brigitta Ursula, Patel, Sanjay, Staab, Alexander, Retlich, Silke
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612798/
https://ncbi.nlm.nih.gov/pubmed/23468467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2012-001844
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