Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins

Amphiphile selection is a critical step for structural studies of membrane proteins (MPs). We have developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from conventional detergents and previously developed FAs. The unique FAs stabilize MPs and form relatively s...

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Detalhes bibliográficos
Main Authors: Lee, Sung Chang, Bennett, Brad C., Hong, Wen-Xu, Fu, Yu, Baker, Kent A., Marcoux, Julien, Robinson, Carol V., Ward, Andrew B., Halpert, James R., Stevens, Raymond C., Stout, Charles David, Yeager, Mark J., Zhang, Qinghai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612649/
https://ncbi.nlm.nih.gov/pubmed/23479627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221442110
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