TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons

Toll-like receptors (TLRs) are the central players in innate immunity. In particular, TLR9 initiates inflammatory response by recognizing DNA, imported by infection or released from tissue damage. Inflammation is, however, harmful to terminally differentiated organs, such as the heart and brain, wit...

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Hlavní autoři: Shintani, Yasunori, Kapoor, Amar, Kaneko, Masahiro, Smolenski, Ryszard T., D’Acquisto, Fulvio, Coppen, Steven R., Harada-Shoji, Narumi, Lee, Hack Jae, Thiemermann, Christoph, Takashima, Seiji, Yashiro, Kenta, Suzuki, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612600/
https://ncbi.nlm.nih.gov/pubmed/23479602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219243110
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