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TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons

Toll-like receptors (TLRs) are the central players in innate immunity. In particular, TLR9 initiates inflammatory response by recognizing DNA, imported by infection or released from tissue damage. Inflammation is, however, harmful to terminally differentiated organs, such as the heart and brain, wit...

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Detalhes bibliográficos
Main Authors: Shintani, Yasunori, Kapoor, Amar, Kaneko, Masahiro, Smolenski, Ryszard T., D’Acquisto, Fulvio, Coppen, Steven R., Harada-Shoji, Narumi, Lee, Hack Jae, Thiemermann, Christoph, Takashima, Seiji, Yashiro, Kenta, Suzuki, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612600/
https://ncbi.nlm.nih.gov/pubmed/23479602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219243110
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