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Conditional immortalization of human thyroid epithelial cells: a tool for analysis of oncogene action.

To overcome the difficulty of assessing oncogene action in human epithelial cell types, such as thyroid, which have limited proliferative potential in culture, we have explored the use of temperature-sensitive (ts) mutants of simian virus 40 (SV40) early region to create conditionally immortalized e...

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Detalhes bibliográficos
Main Authors: Wynford-Thomas, D, Bond, J A, Wyllie, F S, Burns, J S, Williams, E D, Jones, T, Sheer, D, Lemoine, N R
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361234/
https://ncbi.nlm.nih.gov/pubmed/1697930
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