Thyroid epithelial cell transformation by a retroviral vector expressing SV40 large T.

A recombinant murine retroviral vector encoding the SV40 virus large T antigen was used to infect stably an immortal line of differentiated rat thyroid epithelial cells, FRTL-5. Expression of SV40 T transformed these cells to anchorage independence and tumorigenicity but did not alter morphology or...

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Bibliografski detalji
Glavni autori: Burns, J. S., Lemoine, L., Lemoine, N. R., Williams, E. D., Wynford-Thomas, D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1989
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247228/
https://ncbi.nlm.nih.gov/pubmed/2544221
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