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Cardiac-specific knockout of ET(A) receptor mitigates low ambient temperature-induced cardiac hypertrophy and contractile dysfunction

Cold exposure is associated with oxidative stress and cardiac dysfunction. The endothelin (ET) system, which plays a key role in myocardial homeostasis, may participate in cold exposure-induced cardiovascular dysfunction. This study was designed to examine the role of ET-1 in cold stress-induced car...

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Autori principali: Zhang, Yingmei, Li, Linlin, Hua, Yinan, Nunn, Jennifer M., Dong, Feng, Yanagisawa, Masashi, Ren, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612005/
https://ncbi.nlm.nih.gov/pubmed/22442497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjs002
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