Distribution of mutations around rearranged heavy-chain antibody variable-region genes.
The mechanism of somatic hypermutation in the variable region of immunoglobulin genes expressed in mammalian B cells is a major unexplained phenomenon in the generation of diversity in the immune system. To evaluate possible mechanisms, the distribution of somatic mutations was examined for a group...
Bewaard in:
| Gepubliceerd in: | Mol Cell Biol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Taylor & Francis
1990
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.10.5187-5196.1990 |
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