Distribution of mutations around rearranged heavy-chain antibody variable-region genes.

The mechanism of somatic hypermutation in the variable region of immunoglobulin genes expressed in mammalian B cells is a major unexplained phenomenon in the generation of diversity in the immune system. To evaluate possible mechanisms, the distribution of somatic mutations was examined for a group...

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izdano v:	Mol Cell Biol
Principais autores:	Both, G W, Taylor, L, Pollard, J W, Steele, E J
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1990
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.10.5187-5196.1990
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