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Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice

PURPOSE: Extracellular matrix remodeling is thought to have profound effects on tissue architecture and associated function. We have shown previously that overexpression of transforming growth factor beta (TGFβ), which stimulates matrix accumulation, results in altered morphology, cataract, and ocul...

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Hlavní autoři: Robertson, Jennifer V., Siwakoti, Anuja, West-Mays, Judith A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Vision 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611945/
https://ncbi.nlm.nih.gov/pubmed/23559862
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