CYP2D6 and UGT2B7 Genotype and Risk of Recurrence in Tamoxifen-Treated Breast Cancer Patients

BACKGROUND: Adjuvant tamoxifen therapy substantially decreases the risk of recurrence and mortality in women with hormone (estrogen and/or progesterone) receptor–positive breast cancer. Previous studies have suggested that metabolic conversion of tamoxifen to endoxifen by cytochrome P450 2D6 (CYP2D6...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rae, James M., Drury, Suzy, Hayes, Daniel F., Stearns, Vered, Thibert, Jacklyn N., Haynes, Ben P., Salter, Janine, Sestak, Ivana, Cuzick, Jack, Dowsett, Mitch
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611934/
https://ncbi.nlm.nih.gov/pubmed/22395643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs126
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados