CYP2D6 and UGT2B7 Genotype and Risk of Recurrence in Tamoxifen-Treated Breast Cancer Patients

BACKGROUND: Adjuvant tamoxifen therapy substantially decreases the risk of recurrence and mortality in women with hormone (estrogen and/or progesterone) receptor–positive breast cancer. Previous studies have suggested that metabolic conversion of tamoxifen to endoxifen by cytochrome P450 2D6 (CYP2D6...

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Detaylı Bibliyografya
Asıl Yazarlar: Rae, James M., Drury, Suzy, Hayes, Daniel F., Stearns, Vered, Thibert, Jacklyn N., Haynes, Ben P., Salter, Janine, Sestak, Ivana, Cuzick, Jack, Dowsett, Mitch
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611934/
https://ncbi.nlm.nih.gov/pubmed/22395643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs126
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