Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution.

Documenti analoghi

• The heterodimeric subunit SRP9/14 of the signal recognition particle functions as permuted single polypeptide chain.
  di: Bovia, F, et al.
  Pubblicazione: (1994)
• The crystal structure of the signal recognition particle Alu RNA binding heterodimer, SRP9/14.
  di: Birse, D E, et al.
  Pubblicazione: (1997)
• The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs.
  di: Bovia, F, et al.
  Pubblicazione: (1995)
• The SRP9/14 subunit of the human signal recognition particle binds to a variety of Alu-like RNAs and with higher affinity than its mouse homolog.
  di: Bovia, F, et al.
  Pubblicazione: (1997)
• Assembly of the Alu domain of the signal recognition particle (SRP): dimerization of the two protein components is required for efficient binding to SRP RNA.
  di: Strub, K, et al.
  Pubblicazione: (1990)