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The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs.

The heterodimeric protein SRP9/14 bound to the Alu sequences of SRP RNA is essential for the translational control function of the signal recognition particle (SRP). The Alu RNAs of primate cells are believed to be derived from SRP RNA and have been shown to bind to an SRP14-related protein in vitro...

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Publicat a:Mol Biol Cell
Autors principals: Bovia, F, Fornallaz, M, Leffers, H, Strub, K
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7542942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.4.471
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