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Plasmodium falciparum synthetic LbL microparticle vaccine elicits protective neutralizing antibody and parasite-specific cellular immune responses

Epitopes of the circumsporozoite (CS) protein of Plasmodium falciparum, the most pathogenic species of the malaria parasite, have been shown to elicit protective immunity in experimental animals and human volunteers. The mechanisms of immunity include parasite-neutralizing antibodies that can inhibi...

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Hlavní autoři: Powell, Thomas J., Tang, Jie, DeRome, Mary E., Mitchell, Robert A., Jacobs, Andrea, Deng, Yanhong, Palath, Naveen, Cardenas, Edwin, Boyd, James G., Nardin, Elizabeth
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611586/
https://ncbi.nlm.nih.gov/pubmed/23481177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.02.027
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