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Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding.

Myogenin is a muscle-specific transcription factor that can activate myogenesis; it belongs to a family of transcription factors that share homology within a basic region and an adjacent helix-loop-helix (HLH) motif. Although myogenin alone binds DNA inefficiently, in the presence of the widely expr...

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Detalhes bibliográficos
Main Authors: Chakraborty, T, Brennan, T J, Li, L, Edmondson, D, Olson, E N
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC361113/
https://ncbi.nlm.nih.gov/pubmed/1646392
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