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Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

The N-terminal serine and four conserved lysine residues near the N-terminus of yeast histone H4 are acetylated. We found that a mutation that changed the fourth lysine to alanine resulted in specific derepression of the silent mating type locus HML, while mutations that altered the N-terminal serin...

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Udgivet i:Mol Cell Biol
Principais autores: Park, E C, Szostak, J W
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361112/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2117703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4932-4934.1990
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