Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.
The N-terminal serine and four conserved lysine residues near the N-terminus of yeast histone H4 are acetylated. We found that a mutation that changed the fourth lysine to alanine resulted in specific derepression of the silent mating type locus HML, while mutations that altered the N-terminal serin...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2117703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.9.4932-4934.1990 |
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