MicroRNA-31 Activates the RAS Pathway and Functions as an Oncogenic MicroRNA in Human Colorectal Cancer by Repressing RAS p21 GTPase Activating Protein 1 (RASA1)

MicroRNAs (miRNAs) are known to play a vital role in colorectal cancer. We found a widespread disruption in miRNA expression during colorectal tumorigenesis using microarray and quantitative RT-PCR analysis; of the 161 miRNAs altered in colorectal cancer compared with normal adjacent tissue samples,...

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Detalhes bibliográficos
Main Authors: Sun, Defang, Yu, Feng, Ma, Yutao, Zhao, Ran, Chen, Xi, Zhu, Jie, Zhang, Chen-Yu, Chen, Jiangning, Zhang, Junfeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611019/
https://ncbi.nlm.nih.gov/pubmed/23322774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367763
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