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A Pathophysiologic Role for Epidermal Growth Factor Receptor in Pemphigus Acantholysis
The pemphigus family of autoimmune bullous disorders is characterized by autoantibody binding to desmoglein 1 and/or 3 (dsg1/dsg3). In this study we show that EGF receptor (EGFR) is activated following pemphigus vulgaris (PV) IgG treatment of primary human keratinocytes and that EGFR activation is d...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3611014/ https://ncbi.nlm.nih.gov/pubmed/23404504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.438010 |
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