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Vestibular Role of KCNQ4 and KCNQ5 K(+) Channels Revealed by Mouse Models

The function of sensory hair cells of the cochlea and vestibular organs depends on an influx of K(+) through apical mechanosensitive ion channels and its subsequent removal over their basolateral membrane. The KCNQ4 (K(v)7.4) K(+) channel, which is mutated in DFNA2 human hearing loss, is expressed i...

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Detalhes bibliográficos
Main Authors: Spitzmaul, Guillermo, Tolosa, Leonardo, Winkelman, Beerend H. J., Heidenreich, Matthias, Frens, Maarten A., Chabbert, Christian, de Zeeuw, Chris I., Jentsch, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611004/
https://ncbi.nlm.nih.gov/pubmed/23408425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433383
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