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EXTL2, a Member of the EXT Family of Tumor Suppressors, Controls Glycosaminoglycan Biosynthesis in a Xylose Kinase-dependent Manner

Mutant alleles of EXT1 or EXT2, two members of the EXT gene family, are causative agents in hereditary multiple exostoses, and their gene products function together as a polymerase in the biosynthesis of heparan sulfate. EXTL2, one of three EXT-like genes in the human genome that are homologous to E...

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Detalhes bibliográficos
Main Authors: Nadanaka, Satomi, Zhou, Shaobo, Kagiyama, Shoji, Shoji, Naoko, Sugahara, Kazuyuki, Sugihara, Kazushi, Asano, Masahide, Kitagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3611003/
https://ncbi.nlm.nih.gov/pubmed/23395820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.416909
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