A nonerythroid GATA-binding protein is required for function of the human preproendothelin-1 promoter in endothelial cells.

Endothelin-1 (ET-1) is a 21-amino-acid peptide synthesized by endothelial cells that has potent vasoconstrictor activity. Human ET-1 is derived from a 212-amino-acid prepropeptide, termed preproendothelin-1 (PPET-1). To identify cis-acting sequences essential for PPET-1 gene transcription, bovine ao...

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Hlavní autoři: Wilson, D B, Dorfman, D M, Orkin, S H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC361096/
https://ncbi.nlm.nih.gov/pubmed/2388628
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