Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins.

Interleukin-5 (IL-5) is produced by T lymphocytes and known to support B-cell growth and eosinophilic differentiation of the progenitor cells. Using ATL-16T cells which express IL-5 mRNA, we have identified a region within the human IL-5 gene promoter that regulates IL-5 gene transcription. This cis...

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Detalhes bibliográficos
Main Authors: Yamagata, T, Nishida, J, Sakai, R, Tanaka, T, Honda, H, Hirano, N, Mano, H, Yazaki, Y, Hirai, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230622/
https://ncbi.nlm.nih.gov/pubmed/7791790
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