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Site Specific Mutation of the Zic2 Locus by Microinjection of TALEN mRNA in Mouse CD1, C3H and C57BL/6J Oocytes

Transcription Activator-Like Effector Nucleases (TALENs) consist of a nuclease domain fused to a DNA binding domain which is engineered to bind to any genomic sequence. These chimeric enzymes can be used to introduce a double strand break at a specific genomic site which then can become the substrat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Davies, Benjamin, Davies, Graham, Preece, Christopher, Puliyadi, Rathi, Szumska, Dorota, Bhattacharya, Shoumo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610929/
https://ncbi.nlm.nih.gov/pubmed/23555929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060216
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