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Tumor-Specific Microsatellite Instability: Do Distinct Mechanisms Underlie the MSI-L and EMAST Phenotypes?

Microsatellite DNA sequences display allele length alterations or microsatellite instability (MSI) in tumor tissues, and MSI is used diagnostically for tumor detection and classification. We discuss the known types of tumor-specific MSI patterns and the relevant mechanisms underlying each pattern. M...

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Détails bibliographiques
Auteurs principaux: Hile, Suzanne E., Shabashev, Samion, Eckert, Kristin A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610773/
https://ncbi.nlm.nih.gov/pubmed/23206442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2012.11.003
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