Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung

Pneumococcal carriage is both immunising and a pre-requisite for mucosal and systemic disease. Murine models of pneumococcal colonisation show that IL-17A-secreting CD4(+) T-cells (Th-17 cells) are essential for clearance of pneumococci from the nasopharynx. Pneumococcal-responding IL-17A-secreting...

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Bibliografski detalji
Glavni autori: Wright, Adam K. A., Bangert, Mathieu, Gritzfeld, Jenna F., Ferreira, Daniela M., Jambo, Kondwani C., Wright, Angela D., Collins, Andrea M., Gordon, Stephen B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610738/
https://ncbi.nlm.nih.gov/pubmed/23555269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003274
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