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Re-Evaluation of PD-1 Expression by T Cells as a Marker for Immune Exhaustion during SIV Infection

PD-1 expression is generally associated with exhaustion of T cells during chronic viral infections based on the finding that PD-1 expressing cells respond poorly to antigen activation and blockade of PD-1/PD-ligand interaction restores such antigen specific responses in vitro. We tested this hypothe...

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Detalhes bibliográficos
Main Authors: Hong, Jung Joo, Amancha, Praveen K., Rogers, Kenneth, Ansari, Aftab A., Villinger, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610666/
https://ncbi.nlm.nih.gov/pubmed/23555918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060186
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