Spatial Alterations between CD4(+) T(FH), B and CD8(+)T cells during SIV infection: T/B cell homeostasis, activation and potential mechanism for viral escape

HIV/SIV infections induce chronic immune activation with remodeling of lymphoid architecture and hypergammaglobulinemia, although the mechanisms leading to such symptoms remain to be fully elucidated. Moreover, lymph nodes have been highlighted as a predilection site for SIV escape in vivo. Followin...

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Bibliographic Details
Main Authors: Hong, Jung Joo, Amancha, Praveen K, Rogers, Kenneth, Ansari, Aftab A, Villinger, Francois
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311732/
https://ncbi.nlm.nih.gov/pubmed/22387550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103138
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