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Optimal Sparse Segment Identification with Application in Copy Number Variation Analysis

Motivated by DNA copy number variation (CNV) analysis based on high-density single nucleotide polymorphism (SNP) data, we consider the problem of detecting and identifying sparse short segments in a long one-dimensional sequence of data with additive Gaussian white noise, where the number, length an...

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Autori principali: Jeng, X. Jessie, Cai, T. Tony, Li, Hongzhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610602/
https://ncbi.nlm.nih.gov/pubmed/23543902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1198/jasa.2010.tm10083
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