Endoplasmic Reticulum Stress Plays a Pivotal Role in Cell Death Mediated by the Pan-Deacetylase Inhibitor Panobinostat in Human Hepatocellular Cancer Cells

Panobinostat, a pan-deacetylase inhibitor, represents a novel therapeutic option for cancer diseases. Besides its ability to block histone deacetylases (HDACs) by promoting histone hyperacetylation, panobinostat interferes with several cell death pathways providing a potential efficacy against tumor...

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Autores principales: Montalbano, Roberta, Waldegger, Petra, Quint, Karl, Jabari, Samir, Neureiter, Daniel, Illig, Romana, Ocker, Matthias, Di Fazio, Pietro
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610545/
https://ncbi.nlm.nih.gov/pubmed/23544167
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