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The pan-deacetylase inhibitor panobinostat modulates the expression of epithelial-mesenchymal transition markers in hepatocellular carcinoma models

Deacetylase inhibitors (DACis) represent a novel therapeutic option for human cancers by classically affecting proliferation or apoptosis. Since transdifferentiation and dedifferentiation play a key role in carcinogenesis, we investigated the epigenetic influence on the molecular differentiation sta...

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Detalhes bibliográficos
Main Authors: DI FAZIO, PIETRO, MONTALBANO, ROBERTA, QUINT, KARL, ALINGER, BEATE, KEMMERLING, RALF, KIESSLICH, TOBIAS, OCKER, MATTHIAS, NEUREITER, DANIEL
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525501/
https://ncbi.nlm.nih.gov/pubmed/23255907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2012.951
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