Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth

Hemangiosarcoma, a natural model of human angiosarcoma, is an aggressive vascular tumor diagnosed commonly in dogs. The documented expression of several receptor tyrosine kinases (RTKs) by these tumors makes them attractive targets for therapeutic intervention using tyrosine kinase inhibitors (TKIs)...

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Detaylı Bibliyografya
Asıl Yazarlar: Dickerson, Erin B, Marley, Kevin, Edris, Wade, Tyner, Jeffrey W, Schalk, Vidya, MacDonald, Valerie, Loriaux, Marc, Druker, Brian J, Helfand, Stuart C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press Inc. 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610544/
https://ncbi.nlm.nih.gov/pubmed/23544168
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