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The PTEN-AKT3 Signaling Cascade as a Therapeutic Target in Melanoma
Melanocytes undergo extensive genetic changes during transformation into aggressive melanomas. These changes deregulate genes whose aberrant activity promotes the development of this disease. The PI3K (phosphoinositide 3-kinase) and MAP (mitogen-activated protein) kinase pathways are two key signali...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610526/ https://ncbi.nlm.nih.gov/pubmed/19493313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2009.00585.x |
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