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Chimerism and Tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation(1)

The toxicity of chronic immunosuppressive agents required for organ transplant maintenance has prompted investigators to pursue approaches to induce immune tolerance. We developed an approach using a bioengineered mobilized cellular product enriched for hematopoietic stem cells (HSC) and tolerogenic...

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Detalhes bibliográficos
Main Authors: Leventhal, Joseph, Abecassis, Michael, Miller, Joshua, Gallon, Lorenzo, Ravindra, Kadiyala, Tollerud, David J., King, Bradley, Elliott, Mary Jane, Herzig, Geoffrey, Herzig, Roger, Ildstad, Suzanne T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610325/
https://ncbi.nlm.nih.gov/pubmed/22399264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003509
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