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Which factors influence the development of GVHD in HLA-matched or mismatched transplants?

The sheer diversity of HLA alleles makes the probability of finding matched unrelated donors for patients requiring hematopoietic cell transplantation (HCT) a complex situation. New evidence suggests that mismatching at certain HLA loci may provide a greater benefit in terms of graft-versus-leukemia...

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Pubblicato in:Best Pract Res Clin Haematol
Autore principale: Petersdorf, Effie W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967625/
https://ncbi.nlm.nih.gov/pubmed/29156205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2017.09.003
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