Conditional mutations occur predominantly in highly conserved residues of RNA polymerase II subunits.

Conditional mutations in the Saccharomyces cerevisiae RNA polymerase II large subunit, RPB1, were obtained by introducing a mutagenized RPB1 plasmid into yeast cells, selecting for loss of the wild-type RPB1 gene, and screening the cells for heat or cold sensitivity. Sequence analysis of 10 conditio...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Scafe, C, Martin, C, Nonet, M, Podos, S, Okamura, S, Young, R A
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361019/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2406567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.3.1270
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